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SYK 抗体 (pTyr525, pTyr526)

This anti-SYK antibody is a 兔 多克隆 antibody detecting SYK in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7676197
发货至: 中国

Quick Overview for SYK 抗体 (pTyr525, pTyr526) (ABIN7676197)

抗原

See all SYK 抗体
SYK (Spleen tyrosine Kinase (SYK))

适用

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宿主

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克隆类型

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多克隆

标记

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This SYK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    pTyr525, pTyr526

    交叉反应 (详细)

    Expected species reactivity: Mouse,Rat,Pig

    纯化方法

    Antigen affinity purified

    免疫原

    This phospho-Syk antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY525/526 of human Syk.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the phospho-Syk antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the phospho-Syk antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SYK (Spleen tyrosine Kinase (SYK))

    别名

    SYK

    背景

    Syk is a positive effector of BCR-stimulated responses. This protein couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion.

    UniProt

    P43405

    途径

    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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